Of all the amino acids working to keep your body running smoothy, one called glutamine, or L-glutamine, appears to be the most active.
Involved in many processes throughout your body, glutamine is the most abundant amino acid in your blood and muscles. So prevalent, in fact, it makes up 60% of your skeletal muscle.
L-glutamine supports your healthy blood flow as well as your muscle strength, but that’s not all…
It is involved in many vital processes in your body, such as your immune function and gut health, the expression of genes and cell health, and even your hormones.
We’ll look closer at some of the ways L-glutamine may benefit your body, but first, let’s explore why you might be running low on this vital amino acid…
6 Reasons Why You May Be Low on L-Glutamine
Normally your body produces enough glutamine for its regular needs, which makes it a non-essential amino acid.
However, there are times when your body needs more glutamine than it can produce.
When this happens, glutamine becomes a conditionally essential amino acid because you have an increased need that must be met either through diet or by taking an L-glutamine supplement. Here are seven situations when this can occur:
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You’re under a lot of emotional or mental stress.
During periods of stress, your body uses glutamine quickly, which can lead to a glutamine deficiency.
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You exercise intensely.
Strenuous physical exercise can lead to glutamine depletion. Your body produces less glutamine, and your liver and immune cells take up greater amounts during periods of intense exercise.
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You are physically inactive.
Perhaps equally a problem for those who are inactive, healthy volunteers on bed rest in a study experienced reduced synthesis of glutamine, as well as decreased availability to cells and tissues.
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You eat a low-protein diet.
The best sources of glutamine are protein – especially animal proteins – so a low-protein, vegetarian or vegan diet may not provide you with enough.
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You experience periods of intestinal distress.
Glutamine is a major fuel for your intestinal cells and helps protect the lining of your intestinal tract and tight junctions. Heartburn and excess gas may be signs of issues due to low levels of glutamine.
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Your immune system is working overtime.
Whereas your body typically fuels its cells with glucose, your immune system cells – your lymphocytes, neutrophils, and macrophages – use more glutamine than glucose, thus increasing your need for glutamine.
You can get about 3 to 6 g of glutamine from foods if you’re including good sources in your daily diet, such as eggs, whey protein, bone broth, grass fed beef and beef liver, and wild-caught salmon and cod.
If you don’t eat these foods regularly – and you fall into one or more of the groups above with a greater need for glutamine – I recommend adding an L-glutamine supplement to your daily regimen.
How L-Glutamine Can Help When Your Body Becomes Stressed
More than two decades of studies support adding supplemental glutamine to your daily regimen when your body is stressed – situations like we just talked about above.
Researchers have discovered many things… For one, glutamine is an essential fuel for the cells in your intestinal tract and immune system, and no other amino acid can take its place.
They’ve also found that during periods of stress, blood glutamine levels fall. Your gut is particularly affected by low levels of glutamine – the mucous membrane of your small intestine can become atrophic, or waste away.
Adding a glutamine supplement delivers this essential fuel to tissues in need. And because L-glutamine provides the building blocks for protein, it can also help with recovery.*
Here are just a few of the ways you can potentially benefit from L-glutamine:
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Helps maintain muscle strength and helps prevent muscle wasting*
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Aids in recovery and rejuvenation after intense exercise*
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Provides energy for your immune cells for proper immune function*
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Supports digestion and protects the lining of your gastrointestinal tract*
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Helps balance your body’s pH levels*
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Supports brain health as a precursor to the neurotransmitter glutamate*
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Promotes healthy brain aging*
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Fuels your body when it needs more glucose
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Promotes a healthy gut microbiota for weight management*
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Helps maintain already normal blood sugar levels by supporting healthy insulin levels and stabilizing blood glucose*
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Supports healthy detoxification by clearing normal waste products from your body*
Let’s take a closer look at how L-glutamine might help you take your athletic performance to the next level…
Help Banish Fatigue with This “Immune System Fuel”
For athletes – and even non-athletes – there’s nothing more frustrating than feeling fatigued too soon when you’ve set your mind on a task or goal.
Fatigue during physical activity is typically caused by one or more of these factors:
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Depletion of energy sources (such as glycogen)
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Accumulation of protons in your muscle cells
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Oxidative stress
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Muscle damage
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Accumulation of ammonia in your blood and tissues
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An increase in serotonin and decrease in dopamine
A review of data from 55 studies shows that glutamine improves two of these causes of fatigue by increasing glycogen synthesis and reducing the accumulation of ammonia.*
Researchers have recently discovered a connection between amino acids and the onset of fatigue. Studies show that blood levels of glutamine may be reduced in individuals who are overtraining and experiencing fatigue.
What’s more, researchers have also found a connection between overtraining and immune function.
Athletes who train for endurance events, such as marathons, may reduce the amount of glutamine in their bodies, and at the same time, make themselves more vulnerable to seasonal threats.
Some experts think this may be because of the role glutamine plays in the immune system.
For this reason, glutamine has become known as an immune system “fuel,” because a low blood concentration of glutamine can impair your immune cell function.
If you engage in vigorous exercise, you may want to consider supplementing with L-glutamine to not only help avoid fatigue, but also immune system function.*
Boost Your Physical Performance with L-Glutamine
There’s a lot of misunderstanding about glutamine in the world of sports and performance.
Much of that confusion comes down to the form of glutamine – glutamine injections vs. glutamine oral supplements. Unfortunately, some distributors make health claims for their oral glutamine supplements based on studies done with injected glutamine.
Looking only at studies using orally supplemented L-glutamine, the potential benefits for exercise and performance can be divided into four basic categories:
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A decrease in post-exercise intestinal permeability or “leaky gut”*
Physical strain during exercise can lead to increased intestinal permeability and tight junction breakdown, or “leaky gut” as it’s called, which can cause an inflammatory cascade and reduced absorption of nutrients.
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Support an already normal inflammatory response and redox balance post-exercise*
Aging is naturally associated with an increase in proinflammatory immune system cytokines, oxidative stress and depletion of antioxidant defenses which can lead to greater damage to cells, tissues and organs.
Moderate exercise helps counteract these effects, especially in older individuals. In a study with 83 elderly subjects, daily supplementation with L-glutamine enhanced the benefits provided by the assigned exercise program.*
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Reduced reports of post-exercise muscle soreness*
In a study with 16 healthy participants, those taking oral L-glutamine supplements experienced lower soreness ratings after intense exercise.*
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Increased peak torque recovery on eccentric exercise*
Eccentric-phase exercise engages fast twitch muscle fibers more effectively, but it can also cause the greatest degree of muscle hypertrophy, or breakdown, as well as more soreness. L-glutamine supplementation showed the most pronounced effect during movements with longer eccentric phases.*
These benefits can apply to all types of activity, including walking, running, jumping, squatting and weightlifting. The landing phase of walking, running and jumping is the eccentric phase of the action, when most injuries occur.
Could L-Glutamine Increase Your Gut Comfort?
The biochemist who discovered the Krebs cycle and awarded the 1953 Nobel Prize for Physiology – Sir Hans Adolf Krebs – was the first person to recommend taking L-glutamine for gut issues because of its effects on the immune response.*
Glutamine is a major fuel for the cells in your intestines. It helps…
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Regulate the rate of cell growth in your intestine.*
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Modulate signaling in key inflammatory pathways.*
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Protect the lining of your gastrointestinal tract, or mucosa.
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Prevent cell death and cellular stress.*
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Boost immune cell activity in your gut.*
Your gut biome is made up of a precise balance of intestinal bacterial strains that inhabit the fingerlike villi of the single layer of intestinal epithelial cells.
This layer of intestinal cells acts as a defensive barrier to help prevent potentially harmful substances from crossing the cell membranes and reaching your bloodstream.
The space between these cells is sealed by what’s called “tight junctions” and it’s these junctions that control the permeability, or porousness, of your intestinal barrier.
When your gut’s protective barrier becomes compromised for various reasons, you can develop a “leaky” gut. This is when your tight junctions open and allow unwanted substances, like toxins and unwanted invaders, to slip through your gut lining and into your bloodstream.
Excess gas, bloating and indigestion can be signs of a leaky gut.
Unfortunately, your body views these leaked substances as foreign invaders, so it mounts an immune response. This can lead to an improper inflammatory response that spreads throughout your body, sending signals to your brain and affecting all your organ systems.
L-glutamine is readily used by your intestinal tissues, so it can quickly help restore your gut lining to an optimal state – which is great news if you suffer with any gastric complaints or symptoms of intestinal impermeability or leaky gut.*
In a study of 106 individuals who experienced symptoms of leaky, 79.6% of participants who took 5 g of oral L-glutamine daily saw a 50% or greater improvement in their symptoms, which included stool frequency and consistency, compared to only 5.8% of the placebo group.
Help Recharge Your Body with This Go-To Amino Acid
Pure Power L-Glutamine is an unflavored powder that helps keep your body strong even when you face the greatest of challenges.
How does it do that?
By supporting your immune and gut health, as well as promoting a healthy metabolism, L-Glutamine helps recharge your body for the next time you’re in the gym or setting that new personal record.*
Easy-to-mix L-Glutamine supplies 5g of L-Glutamine per scoop. Simply mix one scoop with at least 8 fl. oz. of water or beverage of your choice (ideally cold or lukewarm).
For best results and optimal availability, take L-Glutamine about one-half hour into or after your workout.
There are no fillers or added sugars in our vegan-friendly L-Glutamine, and it contains no dairy, soy, gluten or GMO ingredients.
NSF Certified for Sport® for an Extra Measure of Assurance
Many dietary supplements promise athletes extra strength and power. However, a great deal of them can’t be trusted.
Some of the products do not contain the ingredients or quantities shown on the label, and others may contain unwanted or even banned substances.
With the goal of providing individuals with safer choices when selecting dietary supplements, National Sanitation Foundation (NSF) International has developed the first truly independent testing standard and product certification program known as NSF/ANSI 173.
NSF International’s Certified for Sport® program meets the growing demands of athletes, coaches and all those concerned about banned substances in dietary supplements and functional foods.
Pure Power L-Glutamine is Certified for Sport® by NSF International, the only independent third-party certification program recognized by the United States Anti-Doping Agency (USADA), Major League Baseball, the National Hockey League and the Canadian Football League.
Certified for Sport® is also recommended by the NFL, NBA, PGA, LPGA, CCES, CPSDA, iNADO, Ironman, NASCAR, Taylor Hooton Foundation and many other organizations seeking to mitigate the risks of contaminated dietary supplements.
There are four major quality components of the Certified for Sport® certification program:
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The product is manufactured at a facility that is GMP registered and audited up to two times per year for quality and safety by NSF International to comply with the U.S. FDA’s Good Manufacturing Practice (GMP) requirements.
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Toxicological review of the label to make sure all ingredients are allowed to be in a dietary supplement and that the amount of each ingredient does not exceed typical use levels established by NSF.
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The product and label are tested to verify product formulation and label claims to be sure that what’s on the label is in the product. Then chemical and contaminant testing is conducted to make sure there are no potentially harmful levels of specific contaminants, pesticides, heavy metals and more.
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Products are tested for more than 272 substances which are banned by major athletic organizations and anti-doping associations.
When you choose Pure Power L-Glutamine, you can rest easy knowing it’s a product you can trust.
Build Muscle Even Faster with L-Glutamine and Branched-Chain Amino Acids
Want to experience even greater gains from your workouts? Combine Pure Power L-Glutamine with our premium sports formula Pure Power BCAA + Beta-Alanine.
Branched-chain amino acids (BCAAs) and glutamine are two of the most important protein nutrients for athletes for muscle building and recovery. And that means they can help you perform at your best and recover quickly.*
When taken together – or within a similar time frame – Pure Power L-Glutamine and Pure Power BCAA + Beta-Alanine can help…
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Build muscle better and faster because both provide a valuable source of fuel.*
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Recover faster and reduce your chances of injury.*
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Promote a healthy gut microbiome to support your metabolic health.*
Strong muscles – and peak performance – aren’t just for athletes… Both matter for everyone, even if you lead a sedentary lifestyle. Your muscles help you move, provide you with energy, protect your bones and internal organs, and even play a role in immune health.
Muscles can break down as you grow older and contribute to a loss of muscle mass. This condition, called sarcopenia, increases your risk of injury and disability as well as your loss of independence.
Pure Power L-Glutamine and Pure Power BCAA + Beta-Alanine can help you stay fit and strong, no matter your age. Whether you’re a serious athlete in your prime or you just want to help maintain your healthy muscle mass, this combo package may be the ticket that you’re looking for.
Recharge Your Body and Mind with Pure Power L-Glutamine
To become the strongest version of you – and help you unlock your pure potential – you need the right ingredients.
Each scoop of Pure Power L-Glutamine powder provides 5 g of L-Glutamine that’s easy to mix into any cold or lukewarm beverage.
L-Glutamine supports so many of your body’s processes… Here are just a few of the key benefits you can potentially enjoy…
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Help maintain muscle strength and prevent muscle wasting*
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Recover faster after exercise*
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Support your immune function by providing fuel for your immune cells*
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Help protect the lining of your gastrointestinal tract*
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Promote a healthy gut microbiota for weight management*
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Support your brain health and promote healthy brain aging*
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Help maintain already normal blood sugar levels by supporting healthy insulin levels and stabilizing blood glucose*
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Support detoxification by clearing normal waste products from your body*
No matter your age – or how intensely you work out – Pure Power L-Glutamine can help make a difference in your life.*
Experience the pure power of L-Glutamine, and order your supply today.